The museum replaced the original house in 1966 when it was destroyed by fire. It was rebuilt as a typical traditional Gjirokastrakastra house with many classic features copied from several houses in the city. From 1966 to 1991 the building served as the Anti-Fascist Museum but in 1991 the exhibits from the previous Ethnographic Museum were moved here. The house has four floors, all of which you can visit.

The rooms are arranged as they would have actually been used and are decorated with numerous household items, folk costumes and cultural artefacts typical of a wealthy Gjirokastrakastra family of merchants or of Ottoman administrators living in the town in the 19th Century.