The church, which was originally built on the site of the 5th-century basilica of Arles, is one of the most interesting Romanesque ensembles in Provence. The main features that we see today date back to the 12th-century.
Provence, along with many other regions, developed its own unique Romanesque style, and St. Trophime’s is as good an example as any of this architectural tradition. The sculptures over the church's portal and the columns in the adjacent cloister are considered some of the finest pieces of Romanesque sculpture.
Although the interior is not as decorative as the façade, it is still rich with architectural features covering art from many periods, such as carved Roman sarcophagi, classical Corinthian columns and various Baroque tapestries and paintings. In the 15th-century a Gothic choir was added to the Romanesque nave; impressive in itself at 20 metres high.